http://www.cnr.it/ontology/cnr/individuo/prodotto/ID324640

Cortical activity during olfactory stimulation in multiple chemical sensitivity: a 18F-FDG PET/CT study (Articolo in rivista)

Type

Label

Cortical activity during olfactory stimulation in multiple chemical sensitivity: a 18F-FDG PET/CT study (Articolo in rivista) (literal)

Anno

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

Alternative label

Chiaravalloti A, Pagani M, Micarelli A, Di Pietro B, Genovesi G, Alessandrini M, Schillaci O (2015)
Cortical activity during olfactory stimulation in multiple chemical sensitivity: a 18F-FDG PET/CT study
in European journal of nuclear medicine and molecular imaging (Print); Springer, Berlin Heidelberg (Germania)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Chiaravalloti A, Pagani M, Micarelli A, Di Pietro B, Genovesi G, Alessandrini M, Schillaci O (literal)

Pagina inizio

Pagina fine

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

Rivista

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy Department of Nuclear Medicine Karolinska Hospital Stockholm, Stockholm, Sweden Department of Medical Science and Translational Medicine, University Tor Vergata, Rome, Italy Department of Experimental Medicine, University La Sapienza, Rome, Italy Regional Center for Diagnosis, Treatment and Prevention of MCS, University La Sapienza, Rome, Italy IRCCS Neuromed, Pozzilli, Italy (literal)

Titolo

Cortical activity during olfactory stimulation in multiple chemical sensitivity: a 18F-FDG PET/CT study (literal)

Abstract

Purpose To investigate the differences in brain glucose consumption during olfactory stimulation between subjects affected by multiple chemical sensitivity (MCS) and a group of healthy individuals. Methods Two 18F-FDG PET/CT scans were performed in 26 subjects (6 men and 20 women; mean age 46.7±11 years) with a clinical diagnosis of MCS and in 11 healthy controls (6 women and 5 men; mean age 45.7±11 years), the first scan after a neutral olfactory stimulation (NS) and the second after a pure olfactory stimulation (OS). Differences in 18F-FDG uptake were analysed by statistical parametric mapping (SPM2). Results In controls OS led to an increase in glucose consumption in BA 18 and 19 and a reduction in glucosemetabolismin BA 10, 11, 32 and 47. In MCS subjects, OS led to an increase in glucose consumption in BA 20, 23, 18 and 37 and a reduction in glucose metabolism in BA 8, 9 and 10. Conclusion The results of our study suggest that cortical activity in subjects with MCS differs from that in healthy individuals during olfactory stimulation. (literal)

Editore