Research projects | Consiglio Nazionale delle Ricerche

Institute Experimental Endocrinology and Oncology "Gaetano Salvatore" (IEOMI)

Research projects under the direct responsibility of the Institute
Other research projects in which the Institute collaborates

Research projects under the direct responsibility of the Institute

Unravelling paradoxes in regulatory T cell biology: the molecular basis for an mTOR - dependent oscillatory metabolic switch controlling immune tolerance and autoimmunity (DSB.AD001.052)
Unveiling the role of annexin A1 in Multiple Sclerosis: identification of an endogenous factor decoding T cell breach of the blood brain barrier and immune tolerance (DSB.AD001.054)
IMMUNE CELLS ASSAY TO PREDICT C-PEPTIDE LOSS (DSB.AD001.056)
Identificazione di vettori molecolari per la progettazione di sonde per l'Imaging diagnostico delle patologie oncologiche (DSB.AD001.065)
Phosphomimetic-peptide technology targeting LTCCs: a new tool for modulating conditions of primary and post-inflammatory cardiomyopathy? (DSB.AD001.068)
Meccanismi di regolazione cellulare e molecolare coinvolti nella proliferazione, nel differenziamento e nella trasformazione neoplastica (DSB.AD001.069)
Basi metaboliche del controllo della tolleranza immunologica nella autoimmunità, nell'obesità e nell'infertilità (DSB.AD001.070)
Extracellular microRNAs as molecular link between immune and metabolic dysregulation in Type 1 Diabetes (DSB.AD001.072)
Unveiling the multifaceted activities of BG12 (dimethylfumarate) on immune tolerance through its action on the systemic immunometabolic asset and regulatory T cell functions (DSB.AD001.073)
Unveiling the role of FoxP3 splicing variants in regulatory T cells (Tregs) from subjects with breast cancer (DSB.AD001.080)
Phase I studies of LNA-i-miR-221 and LNA Gapmer 17-92 inhibitor in refractory multiple myeloma patients (DSB.AD001.081)
Role of genetic polymorphism of the cladribine-apoptotic pathway on T cell metabolism and susceptibility to Multiple Sclerosis (DSB.AD001.089)
EFSD CD3+CD56+ cells a novel human regulatory population: function and molecular mechanism in type 1 diabetes (DSB.AD001.091)
AIRC IG grant 2017 - cod. 20095 - Development of a GRASP65/Aurora-A signalling network as a therapeutic target for cancer (DSB.AD001.107)
AIRC LUINI 2018Dissecting and targeting the oncogenic molecular mechanism of action of Golph3, a regulator of Golgi traffic. (DSB.AD001.108)
FISM call 2018 DE ROSA "RUOLO DELLE VESCICOLE EXTRACELLULARI NELLA REGOLAZIONE DELL'ESPRESSIONE DEL FOXP3 E DELLA FUNZIONE SOPPRESSORIA IN CELLULE T REGOLATORIE NELLA SCLEROSI MULTIPLA" (DSB.AD001.137)
PRIN 2017-2017K7FSYB_004-DE ROSA "Stromal-immune cell crosstalk in the generation of tertiary lymphoid structure in solid cancers: immunometabolic aspects and implications for cancer therapy" (DSB.AD001.153)
AIRC-IG Rif.230522019 CERCHIA "DEVELOPMENT of innovative drug-loaded and aptamer targeted nanosystem for treatment of triple-negative breast cancer (DSB.AD001.157)
Contratto Dompè -Gene Profile -SHP1 (DSB.AD001.172)
KAUST University - Computational identification of drugs inhibiting breast cancer stem cells by inducing differentiation (DSB.AD001.179)
FISR2019_00374 -MEDYCA-Disregolazioni del metiloma in cancro: un approccio sinergico multidisciplinare per combatterle (MeDyCa) (DSB.AD001.183)
OCRA Ovarian Cancer Research Alliance Grant Number:813369 "Exploiting PARP-modulating enzymes in ovarian cancer therapy" (DSB.AD001.196)
Ricerca Finalizzata 2018 - Convenzione progetto GR-2018-12367517 - Titolo: Pharmacological targeting of CtBP1/BARS in cancer. (DSB.AD001.205)
Impaired angiogenesis in Diabetes: unravelling the role of Glyoxalase 1 and methylglyoxal (DSB.AD003.020)
MONTE TABOR Genomica del Diabete di tipo II (DSB.AD003.025)
ELI LILLY ITALIA S.p.A. (DSB.AD003.047)
AOU TORINO MIELE"Epigenetic and psychologic correlates of metabolic control in people with type 2 diabetes followed by a long-term structured self-management education program" (DSB.AD003.070)
Cognitive dysfunction in dysmetabolic obesity and diabetes: role of inter-organic crosstalk and cellular ageing (DSB.AD003.083)
H2020-MSCA-ITN-2019 G.A. N. 859962 -SECRET- "Exploitation of the SECRETory pathway for cancer therapy to address European research" (DSB.AD006.273)
CONTRATTO BIOIMAGING CNR - DOMPE' FARMACEUTICI SPA (DSB.AD007.157)
AIRC IG 2018 DE LUCA N. 21420 MICROSCOPIA CORRELATIVA PER L'IMAGING DEL CANCRO (DSB.AD008.489)
PRIN - 2017 20177XJCHX_002 - Daniela CORDA INTEGRATION OF CUTTING-EDGE SPECTROSCOPIC AND IMAGING TECHNIQUES FOR THE STRUCTURAL ANALYSIS OF LIVING-CELL MACHINERIES FROM THE ATOMIC TO THE CELLULAR (DSB.AD008.566)

Other research projects in which the Institute collaborates